Despite the introduction of vaccination, chronic hepatitis B remains a major cause of liver-related morbidity and mortality including cirrhosis, decompensated cirrhosis and hepatocellular carcinoma.Maintenance antiviral therapy is required for most people, as low rates of cure occur.The stated aim of therapy presently is HBV DNA suppression; effect
Abstract Background Self-limited Childhood Epilepsies are the most prevalent epileptic syndrome in children.Its pathogenesis is unknown.In this disease, symptoms resolve spontaneously in approximately 50% of patients when maturity is reached, prompting to a maturation problem.The purpose of this study was to understand the molecular bases of this d
The 1994 Mw 7.1 Mindoro Earthquake and the 2017 Mw 5.9 Batangas Earthquake Sequence both occurred in offshore southern Batangas and devastated southern Luzon and Mindoro.These earthquakes exhibited NW-striking right-lateral slip in an area presumably defined by a WNW-striking left-lateral fault, therefore implying the existence of previously unmapp
Rhabdomyosarcoma (RMS) is a pediatric myogenic-derived soft tissue sarcoma that includes two major histopathological subtypes: embryonal and alveolar.The majority of alveolar RMS expresses PAX3-FOXO1 fusion oncoprotein, associated with the worst prognosis.RMS cells show myogenic markers expression but are unable to terminally differentiate.The Notc